W7167462417 Working papers AI × management and organizations

Agentic Workflow Drift in Life Sciences: Extending the Reasoning-Layer Risk Taxonomy to GxP-Regulated Pharmaceutical and Biotechnology Operations

Maureen Doyle-Spare

Also recorded as: doi:10.2139/ssrn.7301980 · ssrn:7301980

ssrn abstract page · 2026-08-19

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Recorded limitations
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Recorded claims

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The abstract proposes Agentic Workflow Drift as a governance failure in pharmaceutical and biotechnology operations: agentic systems can pass existing validation controls while acting on unauthorized interpretations of regulated terms, and the paper maps proposed reasoning-layer controls onto GxP practice.

confidence: high ssrn-abstract-page apw-e1-ssrn-backfill

Scope: abstract-level; practitioner-led conceptual analysis of regulated organizational operations

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  • abstract-level evidence only; full text not inspected
  • conceptual practitioner-led analysis; the abstract reports no empirical validation
  • the abstract discloses use of a large-language-model assistant for structural editing and terminology/reference consistency checking

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